Date Name Title Filing Type Shares Traded Price Total Held
Oct 01, 2008
SVP, Research & Devel Sciences
SVP, Research & Devel Sciences Form 4 Other acquisition or disposition -- -- 4,275
Sep 25, 2008
Director
Director Form 4 Other acquisition or disposition -- -- 1,822
Sep 22, 2008
SVP, Gen Counsel & Secretary
SVP, Gen Counsel & Secretary Form 4 Other acquisition or disposition -- -- 2,930
Sep 22, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Other acquisition or disposition -- -- 3,127
Sep 22, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Other acquisition or disposition -- -- 8,106
Sep 18, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Other acquisition or disposition -- -- 3,127
Aug 22, 2008
VP, Regul Devel & Med Safety
VP, Regul Devel & Med Safety Form 4 Other acquisition or disposition -- -- 3,127
Feb 28, 2008
Director
Director Form 4 Other acquisition or disposition -- -- 147,505
Feb 28, 2008
Director
Director Form 4 Other acquisition or disposition -- -- 1,676
Dec 21, 2007
Ten Percent Owner
Ten Percent Owner Form 3 Initial Statement of Beneficial Ownership of Securities -- -- 14,799,552

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.