Date Name Title Filing Type Shares Traded Price Total Held
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 700 $806.47 197,248
Mar 23, 2023
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Open market or private sale of non-derivative or derivative security 400 $810.30 196,848
Mar 24, 2023
Director
Director Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,240 $380.95 2,487
Mar 24, 2023
Director
Director Form 4 Open market or private sale of non-derivative or derivative security 1,240 $818.00 1,247
Mar 24, 2023
Director
Director Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 1,240 -- 2,480
Mar 27, 2023
SVP Controller
SVP Controller Form 4 Other acquisition or disposition -- -- 1,473
Mar 27, 2023
SVP Controller
SVP Controller Form 4 Other acquisition or disposition -- -- 5,000
Mar 27, 2023
SVP Controller
SVP Controller Form 4 Other acquisition or disposition -- -- 1,480
Mar 27, 2023
SVP Controller
SVP Controller Form 4 Other acquisition or disposition -- -- 1,897
Mar 27, 2023
SVP Controller
SVP Controller Form 4 Other acquisition or disposition -- -- 461

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.