Date Name Title Filing Type Shares Traded Price Total Held
Aug 21, 2023
Director
Director Form 4 Open market or private sale of non-derivative or derivative security 853 $829.00 1,247
Aug 21, 2023
Director
Director Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 853 -- 854
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 $399.66 103,100
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 38,335 $833.39 64,765
Aug 21, 2023
EVP Research and Development
EVP Research and Development Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 50,000 -- 30,750
Aug 22, 2023
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 6,309 $840.53 58,456
Aug 22, 2023
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 4,574 $841.41 53,882
Aug 22, 2023
EVP Research and Development
EVP Research and Development Form 4 Open market or private sale of non-derivative or derivative security 782 $842.16 53,100
Aug 23, 2023
SVP Controller
SVP Controller Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 7,000 $399.66 26,140
Aug 23, 2023
SVP Controller
SVP Controller Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 5,198 $842.66 20,942

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.