Date Name Title Filing Type Shares Traded Price Total Held
May 20, 2013
SVP Finance and Admin CFO and
SVP Finance and Admin CFO and Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 $16.80 135,803
Nov 21, 2012
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 $16.80 29,372
Nov 21, 2012
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 -- 16,923
Feb 21, 2012
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 $20.32 58,337
Feb 21, 2012
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 -- --
Oct 10, 2011
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 $21.34 20,000
Oct 10, 2011
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 20,000 -- 18,128
Jun 03, 2011
Director
Director Form 4 Bona fide gift 20,000 -- 20,000
Jun 03, 2011
Director
Director Form 4 Bona fide gift 20,000 -- 20,000
Apr 29, 2011
Director
Director Form 4 Conversion of derivative security 20,000 -- 31,875

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.