Date Name Title Filing Type Shares Traded Price Total Held
Mar 07, 2014
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 22,931 $335.06 17,374,158
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,000 $52.03 46,299
Aug 13, 2015
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,000 -- 14,079
May 24, 2022
Director
Director Form 4 Bona fide gift 23,077 -- 322,489
Feb 09, 2024
EVP & General Mgr, Industrial
EVP & General Mgr, Industrial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,125 $381.40 47,153
Feb 09, 2024
EVP & General Mgr, Industrial
EVP & General Mgr, Industrial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,125 -- --
Aug 23, 2023
EVP & General Mgr, Industrial
EVP & General Mgr, Industrial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,125 $381.40 44,633
Aug 23, 2023
EVP & General Mgr, Industrial
EVP & General Mgr, Industrial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,125 -- 23,125
Jan 31, 2012
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,128 $21.92 32,500
Jan 31, 2012
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 23,128 -- 12,500

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.