Date Name Title Filing Type Shares Traded Price Total Held
Jul 17, 2014
Director
Director Form 4 Bona fide gift 14,662 -- 14,662
Feb 16, 2016
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,692 $392.37 23,265,764
Feb 12, 2020
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,722 $402.34 21,658
May 07, 2013
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,750 $16.80 30,074
May 07, 2013
SVP Commercial
SVP Commercial Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,750 -- 2,173
Dec 31, 2003
Director
Director Form 5 Bona fide gift 14,786 $15.10 588,485
Mar 06, 2014
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 14,808 $338.64 17,016,022
Jul 30, 2012
SVP Commercial
SVP Commercial Form 4 Open market or private sale of non-derivative or derivative security 14,833 $135.49 18,306
Feb 17, 2011
SVP F&A, CFO, Treas & Asst Sec
SVP F&A, CFO, Treas & Asst Sec Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,850 $19.43 92,584
Feb 17, 2011
SVP F&A, CFO, Treas & Asst Sec
SVP F&A, CFO, Treas & Asst Sec Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 14,850 -- 16,061

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.