Date Name Title Filing Type Shares Traded Price Total Held
Dec 11, 2017
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 74,860 $383.29 399,847
Aug 20, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 108 $374.46 399,949
May 29, 2020
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private sale of non-derivative or derivative security 2,399,552 $509.85 400,000
Dec 17, 2018
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Other acquisition or disposition -- -- 400,000
Feb 16, 2018
Director, President and CSO
Director, President and CSO Form 4 Bona fide gift 400,000 -- 400,000
Dec 16, 2014
Director, President & CEO
Director, President & CEO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 240,000 -- 400,000
May 15, 2024
Director, Bd. Co-Chair, President & CEO
Director, Bd. Co-Chair, President & CEO Form 4 Open market or private sale of non-derivative or derivative security 295 $980.64 400,041
Jun 21, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Open market or private sale of non-derivative or derivative security 300 $335.01 400,047
Aug 20, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 210 $21.25 400,057
Jul 10, 2018
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Open market or private sale of non-derivative or derivative security 100 $370.17 400,147

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.