Date Name Title Filing Type Shares Traded Price Total Held
Sep 06, 2011
SVP Research and Development S
SVP Research and Development S Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 34,399 $65.76 84,110
Aug 31, 2011
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 143,587 $60.96 309,000
Aug 31, 2011
Director, Chairman of the Board
Director, Chairman of the Board Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 76,458 $60.96 232,542
Aug 15, 2011
SVP Finance and Admin CFO Trea
SVP Finance and Admin CFO Trea Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 3,084 $56.61 89,650
Aug 15, 2011
SVP Finance and Admin CFO Trea
SVP Finance and Admin CFO Trea Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 5,507 $56.61 84,143
Jul 27, 2011
SVP Finance and Admin CFO Trea
SVP Finance and Admin CFO Trea Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 3,919 $53.18 95,778
Jul 27, 2011
SVP Finance and Admin CFO Trea
SVP Finance and Admin CFO Trea Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 8,339 $53.18 87,439
Jul 25, 2011
SVP Clinical Development
SVP Clinical Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 6,949 $56.26 18,051
Jul 25, 2011
SVP Clinical Development
SVP Clinical Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 7,074 $56.26 10,977
Apr 04, 2011
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 26,356 $45.53 116,302

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.