Date Name Title Filing Type Shares Traded Price Total Held
Dec 16, 2011
SVP Finance and Admin CFO Trea
SVP Finance and Admin CFO Trea Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 56,250 -- 87,798
Dec 16, 2011
SVP Finance and Admin CFO Trea
SVP Finance and Admin CFO Trea Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 38,079 -- 38,079
Dec 16, 2011
SVP Gen Counsel and Secretary
SVP Gen Counsel and Secretary Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 4,000 -- 4,000
Dec 16, 2011
VP Controller and Asst Treasur
VP Controller and Asst Treasur Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 1,921 -- 1,921
Dec 16, 2011
VP Controller and Asst Treasur
VP Controller and Asst Treasur Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,579 -- 21,579
Dec 16, 2011
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 1,921 -- 1,921
Dec 16, 2011
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 30,000 -- 45,000
Dec 16, 2011
SVP Clinical Development & Reg
SVP Clinical Development & Reg Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 30,079 -- 30,079
Dec 16, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 1,921 -- 1,921
Dec 16, 2011
VP Regulatory Development and
VP Regulatory Development and Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 28,079 -- 28,079

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.