Date Name Title Filing Type Shares Traded Price Total Held
Dec 14, 2010
SVP Clinical Development
SVP Clinical Development Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 28,736 -- 28,736
Dec 14, 2010
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 3,264 -- 3,264
Dec 14, 2010
VP Regul Devel & Med Safety
VP Regul Devel & Med Safety Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 26,736 -- 26,736
Dec 14, 2010
Director, CEO and President, Ten Percent Owner
Director, CEO and President, Ten Percent Owner Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 125,000 -- 125,000
Dec 14, 2010
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 3,264 -- 3,264
Dec 14, 2010
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 46,736 -- 46,736
Dec 14, 2010
SVP Res and Dev Sciences
SVP Res and Dev Sciences Form 4/A Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 50,350
Dec 14, 2010
SVP Commercial
SVP Commercial Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 3,264 -- 3,264
Dec 14, 2010
SVP Commercial
SVP Commercial Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 29,236 -- 29,236
Dec 14, 2010
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 3,264 -- 3,264

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.