Date Name Title Filing Type Shares Traded Price Total Held
Apr 02, 2020
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,317 $492.05 26,409
Apr 01, 2020
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,936 $488.22 24,937
Apr 01, 2020
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,549 $488.22 25,388
Apr 01, 2020
EVP Finance CFO
EVP Finance CFO Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 1,162 $488.20 25,726
Apr 01, 2020
EVP General Counsel and Secret
EVP General Counsel and Secret Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,757 $488.22 16,681
Apr 01, 2020
EVP General Counsel and Secret
EVP General Counsel and Secret Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,757 $488.22 18,924
Apr 01, 2020
EVP General Counsel and Secret
EVP General Counsel and Secret Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 2,689 $488.22 21,235
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 50,545 $476.42 563,990
Mar 09, 2020
Director, President and Chief Scientific
Director, President and Chief Scientific Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 78,376 $476.42 635,614
Feb 26, 2020
EVP Research and Development
EVP Research and Development Form 4 Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 14,651 $451.89 21,729

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.