Date Name Title Filing Type Shares Traded Price Total Held
Dec 19, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 82,818 -- 82,818
Dec 19, 2005
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 8,591 -- 8,591
Dec 19, 2005
Director
Director Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 303,909 -- 303,909
Dec 19, 2005
Director, EVP, CSO, & Pres Regn Res Labs
Director, EVP, CSO, & Pres Regn Res Labs Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 17,182 -- 17,182
Dec 19, 2005
Director, EVP, CSO, & Pres Regn Res Labs
Director, EVP, CSO, & Pres Regn Res Labs Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 182,818 -- 182,818
Nov 18, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Bona fide gift 500 -- 4,871
Nov 08, 2005
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private sale of non-derivative or derivative security 7,527,050 $11.06 --
Sep 26, 2005
Director
Director Form 4 Bona fide gift 25,544 -- 415,424
Aug 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Open market or private sale of non-derivative or derivative security 1,950 $9.42 14,098
Aug 05, 2005
SVP, PreclinDevel & Biomol Sci
SVP, PreclinDevel & Biomol Sci Form 4 Open market or private sale of non-derivative or derivative security 2,881 $9.43 11,217

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.