| Date | Name | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| Nov 07, 2016 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Bona fide gift | 7,876 | -- | 23,950 |
| Feb 19, 2016 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Bona fide gift | 1,500 | -- | 40,470 |
| Dec 18, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Other acquisition or disposition | -- | -- | 14,376 |
| Dec 18, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Other acquisition or disposition | -- | -- | 5,599 |
| Dec 18, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Other acquisition or disposition | -- | -- | 6,356 |
| Dec 16, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 1,921 | $52.03 | 27,594 |
| Dec 16, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 1,921 | -- | -- |
| Dec 16, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 68,638 | -- | 68,638 |
| Nov 09, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Open market or private sale of non-derivative or derivative security | 9,694 | $558.37 | 34,436 |
| Nov 09, 2015 |
EVP Research and Development
|
EVP Research and Development | Form 4 | Open market or private sale of non-derivative or derivative security | 1,500 | $559.26 | 32,936 |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.