| Date | Name | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| Dec 19, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Other acquisition or disposition | -- | -- | 25,714 |
| Dec 19, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Other acquisition or disposition | -- | -- | 1,674 |
| Dec 16, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Grant, award or other acquisition pursuant to Rule 16b-3(d) | 5,000 | -- | 5,000 |
| May 16, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Bona fide gift | 2,459 | -- | 2,459 |
| May 16, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Bona fide gift | 2,459 | -- | -- |
| May 16, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Bona fide gift | 2,459 | -- | 2,459 |
| May 16, 2016 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Bona fide gift | 2,459 | -- | 2,459 |
| Dec 18, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Other acquisition or disposition | -- | -- | 12,890 |
| Dec 18, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Other acquisition or disposition | -- | -- | 1,652 |
| Dec 16, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 1,921 | $52.03 | 17,742 |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.