| Date | Name | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| Jan 03, 2013 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Open market or private sale of non-derivative or derivative security | 4,300 | $183.10 | 14,990 |
| Jan 02, 2013 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 30,000 | $21.25 | 44,990 |
| Jan 02, 2013 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 3,584 | $177.82 | 41,406 |
| Jan 02, 2013 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 12,830 | $177.82 | 28,576 |
| Jan 02, 2013 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 30,000 | -- | 295 |
| Dec 20, 2012 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Open market or private sale of non-derivative or derivative security | 4,623 | $170.44 | 16,990 |
| Dec 20, 2012 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Open market or private sale of non-derivative or derivative security | 2,000 | $171.11 | 14,990 |
| Dec 20, 2012 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Other acquisition or disposition | -- | -- | 1,532 |
| Dec 19, 2012 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Open market or private sale of non-derivative or derivative security | 1,034 | $176.79 | 30,935 |
| Dec 19, 2012 |
SVP Clin Devel & Reg Affairs
|
SVP Clin Devel & Reg Affairs | Form 4 | Open market or private sale of non-derivative or derivative security | 4,266 | $177.52 | 26,669 |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.