| Date | Name | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 23,000 | $52.03 | 46,299 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 2,065 | $579.35 | 44,234 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 10,795 | $579.35 | 33,439 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 8,000 | $52.03 | 41,439 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 718 | $579.35 | 40,721 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 3,755 | $579.35 | 36,966 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 4,736 | $30.63 | 41,702 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 250 | $579.35 | 41,452 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 2,146 | $579.35 | 39,306 |
| Aug 13, 2015 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 4,736 | -- | -- |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.