| Date | Name | Title | Filing | Type | Shares Traded | Price | Total Held |
|---|---|---|---|---|---|---|---|
| Dec 18, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Open market or private sale of non-derivative or derivative security | 9,000 | $270.20 | 20,742 |
| Dec 18, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 295 | $21.25 | 21,037 |
| Dec 18, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 23 | $264.86 | 21,014 |
| Dec 18, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 139 | $264.86 | 20,875 |
| Dec 18, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 295 | -- | -- |
| Dec 17, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Open market or private sale of non-derivative or derivative security | 8 | $270.00 | 29,742 |
| Dec 17, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Other acquisition or disposition | -- | -- | 1,589 |
| Dec 16, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | 8,000 | $52.03 | 28,742 |
| Dec 16, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 1,526 | $272.73 | 27,216 |
| Dec 16, 2013 |
SVP Clinical Development & Reg
|
SVP Clinical Development & Reg | Form 4 | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 | 3,338 | $272.73 | 23,878 |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.